Author

James R. Henstock

University of LiverpoolORCID 0000-0002-8517-0679Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Research Focus:development & morphogenesis· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Organism:chicken / avian· 1 Assay:organoid / primary culture· 1 Assay:proteomics· 1

Frequent Co-Authors

Anne McArdleiD· 2 shared Christopher McArdle· 2 shared Georgi Olentsenko· 2 shared Gianluca Neri· 2 shared Kai F. HoettgesiD· 2 shared Malcolm Joseph JacksoniD· 2 shared Shahjahan M. Shigdar· 2 shared William Blackler· 2 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersPhysiology

Anne McArdleORCID

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Author profile →

3 papers

Recent·Most cited

MicroAge Mission: Effects of Microgravity and Heat Shock Protein 10 Overexpression on the Proteome of Human Tissue-Engineered Muscle Constructs - Implications for Skeletal Muscle Ageing

S H Jones, Megan Hasoon, Kareena Adair, Shahjahan M. Shigdar, Kay Hemmings, James R. Henstock, Philip Brownridge, Christopher McArdle, Gianluca Neri, William Blackler, Georgi Olentsenko, Andrew R. Jones, Claire E. Eyers, Kai F. Hoettges, Malcolm Joseph Jackson, Anne McArdle

This study examines proteomic changes in human muscle constructs under microgravity and shows that HSP10 overexpression reduces these changes, suggesting a potential strategy for combating muscle atrophy.

bioRxiv · Apr 30, 2026 · PreprintPhysiology

MicroAge Mission: Experimental Design, Hardware Development and Operational Considerations for a Bespoke Culture System to Support Tissue-Engineered Skeletal Muscle Constructs.

Samantha W. Jones, Shahjahan M. Shigdar, Jonathan Temple, Benjamin R. Tollitt, Adam J Janvier, Fiona Mutter, James R. Henstock, Jessica Ohana, David A. Turner, Christopher McArdle, Gianluca Neri, William Blackler, Georgi Olentsenko, Kai F. Hoettges, Anne McArdle, Malcolm Joseph Jackson

The paper describes the design and operational considerations of a tissue-engineered skeletal muscle system for microgravity experiments to study muscle atrophy and aging mechanisms.

npj Microgravity · Feb 21, 2026Peer-reviewedBioengineering

Localized Delivery of Growth Factors from Microparticles Modulate Osteogenic and Chondrogenic Gene Expression in Growth Factor-dependent Manner in an ex vivo Chick Embryonic Bone Model.

Hassan Rashidi, Helen C. Cox, Omar Qutachi, DALE A. MOULDING, Lisa J. White, Emma L. Smith, Janos M. Kanczler, Luís Rojo, Michael Rotherham, James R. Henstock, Molly M. Stevens, Alicia Jennifer El Haj, Richard O. C. Oreffo, Kevin M. Shakesheff, Felicity R. A. J. Rose

The paper develops an ex vivo chick embryonic bone model using PLGA microparticles to study growth factor delivery effects on cell differentiation and tissue formation, showing that controlled release of BMP2 and FGF2 alters collagen deposition and cell morphology.

Acta Biomaterialia · Aug 13, 2025Peer-reviewedBioengineering