Christian Crouzet

High-speed quantitative optical imaging of absolute metabolism in the rat cortex

This paper introduces a method to measure absolute cerebral metabolic rate of oxygen in rat brains using optical imaging techniques and validates it against MR and PET measurements.

Cerebral perfusion and metabolism coupling during a critical time window provides rapid assessment of cardiac arrest severity and prognosis in a preclinical model

The paper measures cerebral perfusion and metabolism metrics post-cardiac arrest in rats to assess severity and prognosis, finding that CBF/CMRO2 ratio at 1 min post-resuscitation predicts neurological recovery with 87% accuracy.

Spreading depolarization and repolarization during cardiac arrest as an ultra-early marker of neurological recovery in a preclinical model

The paper characterizes spreading depolarization and repolarization during cardiac arrest in a rodent model and links their timing to neurological recovery outcomes.