Robert H. Wilson

This paper introduces a method to measure absolute cerebral metabolic rate of oxygen in rat brains using optical imaging techniques and validates it against MR and PET measurements.

The paper measures cerebral perfusion and metabolism metrics post-cardiac arrest in rats to assess severity and prognosis, finding that CBF/CMRO2 ratio at 1 min post-resuscitation predicts neurological recovery with 87% accuracy.

The paper characterizes spreading depolarization and repolarization during cardiac arrest in a rodent model and links their timing to neurological recovery outcomes.