Identification of a weight loss-associated causal eQTL in MTIF3 and the effects of MTIF3 deficiency on human adipocyte function
Mi Ni Huang, Daniel Coral, Hamidreza Ardalani, Peter Spégel, Alham Saadat, Melina Claussnitzer, Hindrik Mulder, Paul W. Franks, Sebastian Kalamajski
The paper identifies a causal eQTL at MTIF3 associated with weight loss and shows MTIF3 deficiency affects adipocyte mitochondrial function and lipid metabolism.
eLife · Mar 6, 2023Peer-reviewedGenetics