Author

Rosalie Heilig

Cancer Research UK Scotland InstituteORCID 0000-0002-8813-9933Unclaimed ORCID profile · follow to get notified of new preprints

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Cell Biology· 1

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Approach:experimental assay· 1

Frequent Co-Authors

Alba Roca-PortolesiD· 1 shared Alfredo Montes Gomes· 1 shared Annabel Black· 1 shared Asma Ahmed· 1 shared Bodhayan Prasad· 1 shared Catherine CloixiD· 1 shared Charlotte E. L. MelloriD· 1 shared Danny Huang· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCell Biology

Alba Roca-PortolesORCID

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1 paper

Recent·Most cited

RNF213 M1-ubiquitinates damaged mitochondria to activate pro-inflammatory NF-κB signaling

Rosalie Heilig, Hannah Glover, Charlotte E. L. Mellor, Catherine Cloix, Michael J. McIlwraith, Lyndsey Flanagan, Nikki R. Paul, Peter Thomason, Bodhayan Prasad, Asma Ahmed, Hugo Dupuis, Destiny Dalseno, Leah Smith, James Hamilton, Ella Hall-Younger, , Stephen WG Tait

This study identifies RNF213 as an E3 ligase that catalyzes M1-linked ubiquitination of damaged mitochondria, activating pro-inflammatory NF-κB signaling through NEMO recruitment.

bioRxiv · Sep 22, 2026 · PreprintCell Biology