Author

Catherine Cloix

Cancer Research UK Scotland InstituteORCID 0000-0001-5666-7558Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

Stephen WG Tait· 2 shared Alba Roca-PortolesiD· 1 shared Alfredo Montes Gomes· 1 shared Annabel Black· 1 shared Asma Ahmed· 1 shared Bodhayan Prasad· 1 shared Charlotte E. L. MelloriD· 1 shared Danny Huang· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersCell Biology

Stephen WG Tait

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2 papers

Recent·Most cited

RNF213 M1-ubiquitinates damaged mitochondria to activate pro-inflammatory NF-κB signaling

Rosalie Heilig, Hannah Glover, Charlotte E. L. Mellor, Catherine Cloix, Michael J. McIlwraith, Lyndsey Flanagan, Nikki R. Paul, Peter Thomason, Bodhayan Prasad, Asma Ahmed, Hugo Dupuis, Destiny Dalseno, Leah Smith, James Hamilton, Ella Hall-Younger, , Stephen WG Tait

This study identifies RNF213 as an E3 ligase that catalyzes M1-linked ubiquitination of damaged mitochondria, activating pro-inflammatory NF-κB signaling through NEMO recruitment.

bioRxiv · Sep 22, 2026 · PreprintCell Biology

Apoptosis-induced FGF signalling promotes non-cell autonomous resistance to cell death

Florian J Bock, Catherine Cloix, Desiree Zerbst, Stephen WG Tait

The paper shows that apoptotic cells release FGF2, which non-cell autonomously upregulates BCL-2 and protects neighboring cells from apoptosis, correlating with worse cancer prognosis.

bioRxiv · Jul 12, 2020 · PreprintCell Biology