Author

Melissa D. Parker

Scripps Research InstituteORCID 0000-0002-8816-8355Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:yeast· 1

Frequent Co-Authors

Katrin KarbsteiniD· 2 shared Adam J. GetzleriD· 1 shared Bogusława KoronaiD· 1 shared Elise S. Brunk· 1 shared Homa GhaleiiD· 1 shared Jason C. CollinsiD· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 9 mutual co-author links

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2 shared papersMolecular Biology

Katrin KarbsteinORCID

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2 papers

Recent·Most cited

The kinase Rio1 and a ribosome collision-dependent decay pathway survey the integrity of 18S rRNA cleavage

Melissa D. Parker, Elise S. Brunk, Adam J. Getzler, Katrin Karbstein

The paper investigates how Rio1 monitors 18S rRNA cleavage quality and prevents miscleaved rRNA from causing translation defects through ribosome collisions.

PLoS Biology · Apr 25, 2024Peer-reviewedMolecular Biology

A kinase-dependent checkpoint prevents escape of immature ribosomes into the translating pool

Melissa D. Parker, Jason C. Collins, Bogusława Korona, Homa Ghalei, Katrin Karbstein

The paper identifies a kinase-dependent checkpoint involving Rio1, Nob1, and Pno1 that prevents immature ribosomes from entering the translating pool, ensuring proper maturation and preventing fidelity defects.

PLoS Biology · Dec 13, 2019Peer-reviewedMolecular Biology