Tao Liu

This study investigates the role of SoxC transcription factors in retinal development, showing they regulate multiple early retinal lineages and function alongside Atoh7 to promote retinal ganglion cell genesis.

This study identifies STAG2's role in regulating chromatin architecture and gene expression in muscle invasive bladder cancer, revealing its context-specific activation and repression of genes involved in oncogenic signaling.

This study identifies key transcription factors that regulate the epigenetic landscape during retinal cell differentiation using scATAC-seq and CUT&Tag.

This paper identifies causal SNPs and their target genes in JIA risk haplotypes using MPRA and CRISPRi, finding 84 SNPs that alter gene expression and regulate multiple genes in TRAF1 and LNPEP/ERAP2 loci.

Chromap provides a fast and accurate method for aligning and preprocessing chromatin profiles, outperforming existing tools in speed while maintaining alignment accuracy.

The paper uses single-cell RNA-seq to analyze retinal ganglion cell lineage development in wild-type and Atoh7-null retinas, revealing a transitional cell state and revised understanding of Atoh7's role.