Fuguo Wu

This study identifies key transcription factors that regulate the epigenetic landscape during retinal cell differentiation using scATAC-seq and CUT&Tag.

The paper uses single-cell RNA-seq to analyze retinal ganglion cell lineage development in wild-type and Atoh7-null retinas, revealing a transitional cell state and revised understanding of Atoh7's role.

This study shows that Zfp36l1 and Zfp36l2 regulate retinal development by balancing proliferation and differentiation, with their loss causing reduced proliferation and increased differentiation in the retina.