End-To-End, Fully Automated Manufacturing of Hematopoietic Stem and Progenitor Cell Therapy Via CCR5-Targeted Integration
Jack M.P. Castelli, Nowah Kokou Apeadoufia Afangbedji, Sofia E. Luna…·Matthew Hebden Porteus
This paper demonstrates an automated, high-throughput platform for manufacturing gene-edited hematopoietic stem and progenitor cells (geHSPCs) with preserved function and in vivo engraftment capacity.