Junjie Ma

The paper introduces snCED-seq, a method for isolating high-quality nuclei from FFPE tissues, showing improved RNA retention and gene detection compared to traditional methods.

This study evaluates how fixation and storage times affect nuclear transcriptomic profiles in FFPE brain tissues, finding that fixation time has a greater impact than storage time.

This study uses single-nucleus RNA sequencing to identify PD-specific cell states in MPTP-induced mouse brains, revealing changes in astrocytes, endothelial cells, and medium spiny neurons.