Chao Jiang

This study shows that hepatocyte MLKL promotes obesity-driven MASLD-HCC through mitochondrial dysfunction and MFN2 suppression, independent of necroptosis.

This study shows that MLKL in hepatocytes promotes liver aging by inducing senescence and mitochondrial dysfunction without causing necroptosis.

This study uses snRNA-seq to analyze how post-mortem interval affects cellular components and gene expression in mouse brain tissues.

This study uses single-nucleus RNA sequencing to identify PD-specific cell states in MPTP-induced mouse brains, revealing changes in astrocytes, endothelial cells, and medium spiny neurons.