Diana Schenkwein

This study optimizes VSV-G-pseudotyped lentiviral transduction of NK cells by improving activation, construct design, and enhancer use, achieving high efficiency without compromising cell function.

This study evaluates engineered K562 feeder cells for enhancing NK cell expansion and function in ex vivo cultures, showing up to 500-fold higher yields compared to feeder-free systems.

The paper identifies drugs that rewiring the cancer-immune interface by enhancing NK cell function and tumor susceptibility through multimodal screening approaches.