Author

Henrik Paavilainen

Orion Corporation (Finland)ORCID 0000-0001-9213-0803Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Diana SchenkweiniD· 2 shared Emmi JärveläiD· 2 shared Erja KerkeläiD· 2 shared Farhana JahaniD· 2 shared Helka GöösiD· 2 shared Jan KoskiiD· 2 shared Kim K. VettenrantaiD· 2 shared Lotta Andersson· 2 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersImmunology

Diana SchenkweinORCID

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2 papers

Recent·Most cited

Efficient NK cell transduction with VSV-G-pseudotyped lentiviral vectors

Emmi Järvelä, Jan Koski, Farhana Jahan, Antti Tuhkala, Mira Saari, Manar Elmadani, Kari Salokas, Laurens Veltman, Lotta Andersson, Erja Kerkelä, Hekim Can, Marie C. Nyman, Seppo Ylä-Herttuala, Markku T Varjosalo, Diana Schenkwein, , Helka Göös

This study optimizes VSV-G-pseudotyped lentiviral transduction of NK cells by improving activation, construct design, and enhancer use, achieving high efficiency without compromising cell function.

Molecular Therapy Advances · May 5, 2026Peer-reviewedImmunology

Feeder cell - the key component in producing scalable and fit NK cells for therapeutic use

Mira Saari, Farhana Jahan, Lotta Andersson, Anna Syreeni, Pirjo Vehmaan-Kreula, Jan Koski, Emmi Järvelä, Erja Kerkelä, Henrik Paavilainen, Diana Schenkwein, Seppo Ylä-Herttuala, Kim K. Vettenranta, Helka Göös, Matti Korhonen

This study evaluates engineered K562 feeder cells for enhancing NK cell expansion and function in ex vivo cultures, showing up to 500-fold higher yields compared to feeder-free systems.

bioRxiv · Apr 23, 2026 · PreprintImmunology