Author

Monika M. A. Karney

University of Nevada, Las VegasORCID 0000-0002-8863-7676Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 3 Approach:experimental assay· 3 Approach:statistical model· 1

Frequent Co-Authors

Helen J. WingiD· 3 shared Taylor M. GersoniD· 3 shared Alexander D. KarabacheviD· 1 shared Audrey M. Ott· 1 shared Daren R. Ginete· 1 shared Jillian N. SoceaiD· 1 shared Joy A. McKennaiD· 1 shared Juan Carlos DuhartiD· 1 shared

Activity by Year

2023-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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3 shared papersMolecular Biology

Helen J. WingORCID

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3 papers

Recent·Most cited

Molecular BiologyNucleic Acids ResearchPeer-reviewedJan 31, 2026

The role of the VirB ligand CTP in the molecular mechanism of transcriptional anti-silencing in Shigella flexneri

Taylor M. Gerson, Monika M. A. Karney, Helen J. Wing

This study investigates the role of CTP in VirB's anti-silencing mechanism in Shigella flexneri, showing CTP is necessary for large VirB-DNA complex formation and DNA supercoil loss.

DOI 10.1093/nar/gkag115

bacteria (other)experimental assay

𝕏 PostBluesky

MicrobiologymBioPeer-reviewedSep 20, 2023

VirB, a key transcriptional regulator of Shigella virulence, requires a CTP ligand for its regulatory activities

Taylor M. Gerson, Audrey M. Ott, Monika M. A. Karney…·Helen J. Wing

This paper identifies CTP as a ligand for the Shigella virulence regulator VirB, showing that CTP binding is essential for its regulatory functions and virulence phenotypes.

16 citations

bacteria (other)statistical model

𝕏 PostBluesky

Molecular BiologyNucleic Acids ResearchPeer-reviewedJan 31, 2023

Localized modulation of DNA supercoiling, triggered by the Shigella anti-silencer VirB, is sufficient to relieve H-NS-mediated silencing

Michael A. Picker, Monika M. A. Karney, Taylor M. Gerson…·Helen J. Wing

The paper shows VirB modulates DNA supercoiling to relieve H-NS-mediated silencing in Shigella, independent of transcription or H-NS presence.

29 citationstop 3%

bacteria (other)experimental assay

𝕏 PostBluesky