A Human Brain Map of Mitochondrial Respiratory Capacity and Diversity
Eugene V. Mosharov, Ayelet M Rosenberg, Anna Sophia Monzel, Corey A. Osto, Linsey Stiles, Gorazd B. Rosoklija, Andrew J. Dwork, Snehal Bindra, Alex Junker, Ya Zhang, Masashi Fujita, Madeline B. Mariani, Mihran J. Bakalian, David L. Sulzer, Philip L. De Jager, , Martin A. Picard
The paper creates a brain-wide map of mitochondrial phenotypes by combining physical voxelization with biochemical profiling, revealing regional differences in mitochondrial density and function.
Nature · Mar 26, 2025Peer-reviewedNeuroscience