Author

Jonathan LaCombe

LabCorp (United States)ORCID 0000-0002-8867-6018Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1 Approach:statistical model· 1 Research Focus:trajectory inference· 1

Frequent Co-Authors

Isabella Crawford· 1 shared Jared R. Thomas· 1 shared Joseph Michael WallaceiD· 1 shared Kourtney SloaniD· 1 shared Matthew P. Blackwell· 1 shared Randall J. RoperiD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

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6 top collaborators · 15 mutual co-author links

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1 shared paperGenetics

Isabella Crawford

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1 paper

Recent·Most cited

GeneticsbioRxivPreprintMay 24, 2024

Sex specific emergence of trisomic Dyrk1a-related skeletal phenotypes in the development of a Down syndrome mouse model

Jonathan LaCombe, Kourtney Sloan, Jared R. Thomas…·Randall J. Roper

The paper analyzes bone development and gene expression in Ts65Dn mice to identify timepoints when trisomic Dyrk1a overexpression links to skeletal abnormalities, showing sex-dependent differences in deficit timing and resolution.

4 citations

mousebulk RNA-seq

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