Author

Kourtney Sloan

Indiana University IndianapolisORCID 0009-0004-3552-6085Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:mouse· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Research Focus:trajectory inference· 1

Frequent Co-Authors

Joseph Michael WallaceiD· 2 shared Randall J. RoperiD· 2 shared Charles R. GoodlettiD· 1 shared Gayla R. OlbrichtiD· 1 shared Isabella Crawford· 1 shared Jared R. Thomas· 1 shared Jonathan LaCombeiD· 1 shared Kristina M. Piner· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersGenetics

Joseph Michael WallaceORCID

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2 papers

Recent·Most cited

Genetic analysis of triplicated genes affecting sex-specific skeletal deficits in Down syndrome model mice

Kourtney Sloan, Kristina M. Piner, Pathum Randunu Nawarathna Kandedura Arachchige, Charles R. Goodlett, Yann Hérault, Gayla R. Olbricht, Joseph Michael Wallace, Randall J. Roper

The paper compares skeletal phenotypes between two Down syndrome mouse models, Ts65Dn and Ts66Yah, using a novel PCA-based method to assess the impact of non-Hsa21 trisomic genes on bone structure and function.

G3 Genes Genomes Genetics · Mar 6, 2026Peer-reviewedGenetics

Sex specific emergence of trisomic Dyrk1a-related skeletal phenotypes in the development of a Down syndrome mouse model

Jonathan LaCombe, Kourtney Sloan, Jared R. Thomas, Matthew P. Blackwell, Isabella Crawford, Joseph Michael Wallace, Randall J. Roper

The paper analyzes bone development and gene expression in Ts65Dn mice to identify timepoints when trisomic Dyrk1a overexpression links to skeletal abnormalities, showing sex-dependent differences in deficit timing and resolution.

bioRxiv · May 24, 2024 · PreprintGenetics