Kinesin-1 Autoinhibition Tunes Cargo Transport by Motor Ensembles
Brandon M. Bensel, Samantha Beck Previs, Patricia M. Fagnant, Kathleen M. Trybus, Sam Walcott, David M. Warshaw
This study investigates how kinesin-1 autoinhibition affects cargo transport through 3D microtubule intersections, showing that autoinhibited motors reduce MT engagement and alter directional outcomes.
Biophysical Journal · Sep 2, 2025Peer-reviewedBiophysics