Patricia M. Fagnant

This study shows phosphorylated melanophilin biases liposome exit from actin-microtubule intersections toward actin, while dephosphorylated melanophilin biases exit toward microtubules.

This study determines the structure of Plasmodium falciparum MyoB, shows it is a slow motor optimized for force generation during invasion, and identifies its light chain as shared with MyoA.

This study presents the cryo-EM structure of human ATAD2B, revealing its hexameric organization and providing insights into its ATPase activity and substrate coordination.

This study investigates how kinesin-1 autoinhibition affects cargo transport through 3D microtubule intersections, showing that autoinhibited motors reduce MT engagement and alter directional outcomes.

This study shows BicD and MAP7 work together to activate Drosophila kinesin-1 through distinct mechanisms, enhancing motor activity and microtubule engagement.

This paper identifies a small molecule inhibitor of Plasmodium falciparum myosin A, showing it blocks ATP hydrolysis and parasite growth.

This study identifies an essential light chain for Plasmodium falciparum class XIV myosin that enhances actin motility speed when expressed with the heavy chain and known light chain.