A Consensus Model of Glucose-Stimulated Insulin Secretion in the Pancreatic beta-Cell
M. Deepa Maheshvare, Soumyendu Raha, Matthias König, Debnath Pal
The paper develops a consensus model of glucose-stimulated insulin secretion in pancreatic beta-cells using a systematic workflow, showing glucose-dependent increases in glycolytic intermediates and ATP/ADP ratios drive insulin secretion.