Author

Kalle H. Sipilä

Guy's HospitalORCID 0000-0002-8882-3786Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Developmental Biology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:human· 1 Approach:simulation· 1

Frequent Co-Authors

Emanuel RognoniiD· 2 shared Fiona M. WattiD· 2 shared Angela Oliveira PiscoiD· 1 shared Christina PhilippeosiD· 1 shared Clarisse GânieriD· 1 shared Fuping ZhangiD· 1 shared Johanna JokineniD· 1 shared Julio Monti BelmonteiD· 1 shared

Activity by Year

2018-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersCancer Biology

Emanuel RognoniORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Plasticity of squamous differentiation drives drug resistance in HNSCC

Kalle H. Sipilä, Matteo Vietri Rudan, Priyanka G. Bhosale, Matthew Blakeley, Clarisse Gânier, Robert Kennedy, Emanuel Rognoni, Fiona M. Watt

This study shows that some HNSCC cells resist differentiation despite being capable of it, highlighting a barrier to differentiation-based therapies.

bioRxiv · Mar 11, 2026 · PreprintCancer Biology

Embigin deficiency leads to delayed embryonic lung development and high neonatal mortality

Salli Talvi, Johanna Jokinen, Kalle H. Sipilä, Pekka Rappu, Fuping Zhang, Matti H. POUTANEN, Pia Rantakari, Jyrki Heino

The paper shows that Embigin deficiency causes delayed embryonic lung development and high neonatal mortality in mice.

bioRxiv · Jul 5, 2021 · PreprintDevelopmental Biology

Fibroblast state switching orchestrates dermal maturation and wound healing

Emanuel Rognoni, Angela Oliveira Pisco, Toru Hiratsuka, Kalle H. Sipilä, Julio Monti Belmonte, Seyedeh Atefeh Mobasseri, Christina Philippeos, Rui Dilão, Fiona M. Watt

The paper shows fibroblast state switching between proliferation and ECM deposition defines dermal architecture and is critical for wound healing.

Molecular Systems Biology · Aug 1, 2018Peer-reviewedSystems Biology