Andrew Sofronis Papanastasiou

The paper uses optic vesicle organoids to study gene expression and chromatin changes during eye field specification, identifying key transcription factors and regulatory elements.

The paper identifies distinct cell type-specific functions of two overlapping PAX6 retinal enhancers using live imaging and single-cell RNA sequencing in zebrafish.

This study identifies a critical genomic region on the X chromosome linked to anophthalmia in mice but finds no clear causative mutation, suggesting regulatory changes may underlie the phenotype.