Author

Leander Sützl

BOKU UniversityORCID 0000-0002-8889-2343Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:protein design· 2 Assay:protein sequence· 2 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Approach:statistical model· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Alexandra EssebieriD· 1 shared Álvaro Muñoz‐LópeziD· 1 shared Ariane MoraiD· 1 shared Benjamin SalzeriD· 1 shared Boštjan KobeiD· 1 shared Brad BaldersoniD· 1 shared Burkhard RostiD· 1 shared Charlotte U. ZajciD· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperBioinformatics

Alexandra EssebierORCID

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2 papers

Recent·Most cited

Synthetic BiologybioRxivPreprintSep 9, 2025

MiniCARbids: Minimalistic human binding domains specifically tailored to CAR T applications

Magdalena Teufl, Julia Mayer, Kerstin E. Holzer…·Michael W. Traxlmayr

The paper introduces miniCARbids, small human-derived CAR binding domains that show high anti-tumor potency in CAR T cells, outperforming traditional scFvs in some cases.

1 citation

humanprotein sequence

𝕏 PostBluesky

BioinformaticsPLoS Computational BiologyPeer-reviewedOct 24, 2022

Engineering indel and substitution variants of diverse and ancient enzymes using Graphical Representation of Ancestral Sequence Predictions (GRASP)

Gabriel Foley, Ariane Mora, Connie M. Ross…·Mikael Bodén A

The paper introduces GRASP, a method for ancestral sequence reconstruction that handles large datasets and indels, demonstrating its ability to generate biologically active enzyme ancestors.

70 citationstop 4%

protein sequencestatistical model

𝕏 PostBluesky