Boryana S. Koseva

Expanded map of genomic imprinting reveals insight into human disease

The paper expands the human genomic imprinting map using long-read sequencing and GWAS integration, revealing new disease-associated loci and maternal/paternal imprinting patterns.

Direct haplotype-resolved 5-base HiFi sequencing for genome-wide profiling of hypermethylation outliers in a rare disease cohort

The paper uses HiFi sequencing to identify hypermethylation outliers in a rare disease cohort, finding allele-specific loss of regulatory elements linked to disease.

High-resolution epigenome analysis in nasal samples derived from children with respiratory viral infections reveals striking changes upon SARS-CoV-2 infection

The paper analyzes DNA methylation changes in nasal samples from infants with respiratory viral infections, identifying virus-specific differentially methylated regions and their association with immune responses.

The genome of Drosophila innubila reveals lineage-specific patterns of selection in immune genes

The paper sequences the genome of Drosophila innubila and finds that antiviral RNAi genes evolve slowly, contrasting with Drosophila melanogaster, suggesting different evolutionary pressures for DNA and RNA virus resistance.