Alexsandro Sobreira Galdino

This paper identifies T. cruzi-specific B-cell epitopes using computational methods and experimental validation, achieving high diagnostic accuracy for Chagas disease.

This paper analyzes global research trends on fungal antimicrobials using bibliometric methods, identifying key countries, authors, institutions, and patents.

This study evaluates Malvidin and Echioidinin as antileishmanial agents through in vitro and in silico analyses, finding Malvidin more potent and less toxic than Echioidinin and Amphotericin B.

This study reviews and analyzes preclinical treatments for Chagas disease using animal models, finding promising candidates but limited clinical success.

The paper evaluates natural products for anti-leishmanial activity against Leishmania infantum MOGS using CADD, identifying Ocotillone and Subsessiline as promising candidates with pH-dependent inhibition and favorable ADMET profiles.

This study identifies structural analogs of natural products that target the purine salvage pathway in Leishmania infantum using computer-aided drug design, showing good binding affinity and potential for oral administration.