Séverine Vermeire

This study identifies molecular subtypes of perianal fistulizing Crohn's disease using multiomics, revealing a psoriasis-like keratinization signature linked to surgical outcomes.

This study identifies 619 IBD risk signals, resolves 81 high-confidence variants, and prioritizes 664 candidate effector genes using GWAS, eQTL, and exome sequencing.

This study uses exome and genome sequencing to identify 68 genes directly associated with inflammatory bowel disease, providing clearer genetic insights and therapeutic targets.

The paper investigates resistance to JAK inhibitors in UC by analyzing single-cell RNA data from responders and non-responders, identifying hyperactivation of myeloid cells as a key mechanism.

This study identifies IL-26-expressing MAIT cells as protective for epithelial barrier function and shows their dysregulation in Crohn's disease.

The paper investigates how intestinal inflammation in IBD affects SARS-CoV-2 entry receptors like ACE2, finding opposing regulation in ileum and colon.