Integrated 5-HT2A-TrkB and G protein signaling in serotonergic psychedelic responses
Marco Taddei-Tardon, Lidia Medina-Rodríguez, Jessica L. Maltman, Sarah Hudson, Sritanvi Potukanuma, Javier Hidalgo Jiménez, Sandra M. Martin-Guerrero, Javier González‐Maeso, Juan F. López‐Giménez
This study investigates the molecular mechanisms of serotonergic psychedelics using a neural stem cell model, revealing an integrated 5-HT2A-TrkB signaling network involved in neuroplasticity and metabolic responses.
Molecular Psychiatry · Jul 16, 2026Peer-reviewedNeuroscience