Karolina Chwalek

This paper develops a multi-omic model to predict phenotypic age in mice, showing it can predict remaining lifespan even among same-aged mice.

This study measures technical variability in Illumina DNA methylation microarrays, identifying positional biases and outliers that affect differential methylation testing and predictive modeling.

This paper demonstrates that epigenetic reprogramming using OSK genes can reverse age-related and injury-induced vision loss in mice by resetting DNA methylation patterns and promoting axon regeneration.