Author

Samuel A. Wickline

Washington University in St. LouisORCID 0000-0002-8949-3192Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

Angela C. HirbeiD· 1 shared Antonina M. AkkiD· 1 shared Christine T. N. PhamiD· 1 shared Elisha D. O. RobersoniD· 1 shared Hua PaniD· 1 shared Huimin YaniD· 1 shared Yang LyuiD· 1 shared Ying HuiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

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1 shared paperCell Biology

Angela C. HirbeORCID

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1 paper

Recent·Most cited

Systemic delivery of murine SOD2 mRNA to experimental abdominal aortic aneurysm mitigates expansion and rupture

Huimin Yan, Ying Hu, Yang Lyu, Antonina M. Akk, Angela C. Hirbe, Samuel A. Wickline, Hua Pan, Elisha D. O. Roberson, Christine T. N. Pham

This study delivers SOD2 mRNA via nanoparticles to mice with abdominal aortic aneurysms, reducing aneurysm expansion and rupture by enhancing antioxidant activity and modulating inflammatory pathways.

Theranostics · Mar 10, 2025Peer-reviewedCell Biology