A genotype-first approach identifies variants for orofacial clefts and other phenotypes in dogs
Reuben M. Buckley, Nüket Bilgen, Alex C. Harris, Peter Savolainen, Cafer Tepeli, Metin Erdoğan, Aitor Serres Armero, Dayna L. Dreger, Frank G. van Steenbeek, Marjo K. Hytönen, Jessica J. Hale, Hannes Lohi, Bengi Çınar Kul, Adam R. Boyko, Elaine A. Ostrander
This study uses a genotype-first approach to identify new mutations related to craniofacial morphology and stature in dogs, highlighting the role of allelic heterogeneity in breed trait selection.
bioRxiv · Oct 4, 2024 · PreprintGenomics