Thomas Wälchli

This study identifies Nogo-A as an onco-fetal protein that inhibits glioma vascularization and growth through VEGF-Notch-Hippo-metabolic signaling in human and mouse models.

The paper constructs a molecular atlas of the human brain vasculature using single-cell RNA sequencing, revealing molecular heterogeneity and disease-related alterations in vascular cells.

This paper describes a method to image and analyze 3D vascular networks in mouse brains across development and adulthood, quantifying various vascular features.

This study identifies Nucleolin as a factor reactivated in gliomas that promotes angiogenesis and endothelial metabolism by regulating glycolysis through p53-TIGAR-HK2.

The paper constructs a single-cell atlas of SARS-CoV-2 entry factors and interaction partners in human and mouse brain vasculature, revealing distinct expression patterns of CTSB and CTSL in brain and peripheral vasculature.