Mia A. Rosenfeld

D614G reshapes allosteric networks and opening mechanisms of SARS-CoV-2 spikes

This paper investigates how the D614G mutation in SARS-CoV-2 spike protein alters conformational dynamics and allosteric communication, leading to faster RBD opening and increased infectivity.

Condensate-Like Organization in Respiratory Aerosols Modulates the Dynamics of an Airborne Virus

This study uses molecular dynamics simulations to show how respiratory aerosols create structured microenvironments that influence SARS-CoV-2 stability and spike dynamics.

pH-induced structural changes in SARS-CoV-2 spike variants

This study uses D-NEMD simulations to show how pH changes induce variant-specific conformational changes in SARS-CoV-2 spike proteins, affecting their stability and entry mechanisms.

Breaking Down the Bottlebrush: Atomically-Detailed Structural Dynamics of Mucins

This study uses molecular dynamics simulations to explore the structural dynamics of mucins, revealing how O-glycosylation influences their bottlebrush-like conformation.