Author

Akira Nishii

University of MichiganORCID 0000-0002-8981-3264Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Jessica N. MaungiD· 2 shared Ormond A. MacDougaldiD· 2 shared Aluet Borrego Alvarez· 1 shared Annie JeniD· 1 shared Dustin Baldridge· 1 shared Elif A. Oral· 1 shared Emma Paulsson· 1 shared Hiroyuki MoriiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersGenomics

Jessica N. MaungORCID

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2 papers

Recent·Most cited

An Isogenic iPSC Model of LMNA p.R482W Recapitulates Adipocyte Dysfunction in Familial Partial Lipodystrophy Type 2

Aluet Borrego Alvarez, Will Oliver Wasielewski, McKinlee R.S. Gobble, Michael Grupe, Lina M. Ali, William Buchser, Lauren Boggs-Bailey, Dustin Baldridge, Jessica N. Maung, Akira Nishii, Ormond A. MacDougald, Elif A. Oral, Stephen I. Stone

This paper develops an isogenic iPSC model of FPLD2 carrying the LMNA p.R482W variant, showing adipocyte dysfunction including insulin resistance and metabolic impairment.

bioRxiv · Nov 2, 2026 · PreprintGenomics

SCD1 and monounsaturated lipids are required for autophagy and survival of adipocytes

Hiroyuki Mori, Sydney K. Peterson, Rachel C. Simmermon, Katherine A. Overmyer, Akira Nishii, Emma Paulsson, Ziru Li, Annie Jen, Romina María Uranga, Jessica N. Maung, Warren T. Yacawych, Kenneth T. Lewis, Rebecca L. Schill, Taryn A. Hetrick, Ryo Seino, , Ormond A. MacDougald

This study shows that SCD1 and monounsaturated lipids are essential for autophagy and survival of adipocytes, with SCD1 deficiency causing autophagosome accumulation and cell death.

Molecular Metabolism · Mar 14, 2024Peer-reviewedMolecular Biology