Author

Susanna Pietropaolo

Centre National de la Recherche ScientifiqueORCID 0000-0002-8993-1922Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 4 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Wim E. CrusioiD· 3 shared Eric Louette· 2 shared Marion Piquemal· 2 shared Valérie Lemaire· 2 shared Benjamin J.A. RobertiD· 1 shared Didier DuloniD· 1 shared Jérôme EzaniD· 1 shared Maïté Marie MoreauiD· 1 shared

Activity by Year

2020-2020 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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3 shared papersNeuroscience

Wim E. CrusioORCID

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4 papers

Recent·Most cited

Chlorzoxazone, A BKCa Channel Agonist, Rescues The Pathological Phenotypes Of Williams-Beuren Syndrome In A Preclinical Model

Marion Piquemal, Noura Abdalla, Paula Ortiz‐Romero, Valérie Lemaire, Wim E. Crusio, Eric Louette, Victoria Campuzano, Susanna Pietropaolo

This paper shows that chlorzoxazone, a BKCa channel agonist, improves multiple pathological features in a mouse model of Williams-Beuren syndrome.

bioRxiv · Dec 22, 2020 · PreprintNeuroscience

Therapeutic effects of Chlorzoxazone, a BKCa channel agonist, in a mouse model of Fragile X syndrome

Valérie Lemaire, Marion Piquemal, Wim E. Crusio, Eric Louette, Susanna Pietropaolo

This study evaluates the therapeutic effects of chlorzoxazone, a BKCa channel agonist, on FXS-like symptoms in Fmr1-KO mice, showing its efficacy in treating multiple behavioral abnormalities.

bioRxiv · Dec 11, 2020 · PreprintNeuroscience

Scribble controls social behaviors through the regulation of the ERK/Mnk1 pathway

Maïté Marie Moreau, Susanna Pietropaolo, Jérôme Ezan, Benjamin J.A. Robert, Sylvain Miraux, Marlène Maître, Yoon H. Cho, Wim E. Crusio, Mireille Montcouquiol, Nathalie Sans

This study investigates the role of the Scribble gene in social behaviors, finding that its mutation leads to social deficits linked to the ERK/Mnk1 pathway and hippocampal dysfunction.

bioRxiv · Sep 10, 2020 · PreprintNeuroscience

SYNAPTIC RELEASE POTENTIATION AT AGING AUDITORY RIBBON SYNAPSES

Thibault Peineau, Séverin Belleudy, Susanna Pietropaolo, Yohan Bouleau, Didier Dulon

The paper investigates age-related changes in auditory ribbon synapses of mice, finding increased synaptic transmission and potential compensation for synapse loss.

bioRxiv · May 15, 2020 · PreprintNeuroscience