Jérôme Ezan

This study identifies Dvl2 as a novel component of the axon initial segment (AIS) and reveals its role in AIS assembly through MTCL1-dependent microtubule recruitment.

The paper identifies a female-specific microglial redox program that influences susceptibility to obesity by modulating metabolic resilience and mTORC1 signaling.

This study identifies Vangl2 as essential for the morphogenesis and function of MfB/TE synapses in the hippocampus and shows its role in declarative memory processes.

This study shows that Scrib deletion in mice causes cortical thinning, disrupted connectivity, and psychomotor deficits, linking Scrib to neurodevelopmental disorders.

This study investigates the role of the Scribble gene in social behaviors, finding that its mutation leads to social deficits linked to the ERK/Mnk1 pathway and hippocampal dysfunction.