Nicholas C. Fitzkee

Mapping the vRNA Interaction with HIV-1 Integrase

The paper maps interactions between HIV-1 Integrase and viral RNA, identifying new critical amino acids in the CTD essential for viral replication and core morphology.

Precision control of nanoparticle delivery with engineered biomimetic protein coronas

This paper engineers biomimetic protein coronas on nanoparticles to improve tumor targeting and reduce immune recognition, achieving 4% ID/g tumor accumulation.

Thermodynamic Analysis of Protein-Nanoparticle Interactions Links Binding Affinity and Structural Stability

The paper investigates how protein charge distribution affects adsorption to polystyrene nanoparticles using lysine-to-alanine variants and finds that removing lysine at position 19 enhances binding and stability.

Using a Bacterial Protein to Selectively Target Bacterial Biofilms: Treatment of S. epidermidis Biofilms with Targeted Photothermal Gold Nanoparticles

This paper develops targeted photothermal gold nanoparticles using a bacterial protein to selectively destroy S. epidermidis biofilms with high efficiency.