Targeting PTRAMP-CSS potently inhibits P. falciparum across blood, liver and mosquito stages
Pailene S. Lim, Nicolai C Jung, Mikha Gabriela, Jelte M. M. Krol, Kitsanapong Reaksudsan, Myo T. Naung, Danushka S. Marapana, Rainbow W.B. Chan, Diana Nyabundi, Jedida Mwacharo, Melissa C. Kapulu, Philip Bejon, Francis Maina Ndungu, Alyssa E. Barry, Rajagopal Murugan, , Stephen W. Scally
This study shows that targeting PTRAMP-CSS inhibits Plasmodium falciparum across liver, blood, and mosquito stages, supporting its potential as a multistage vaccine target.
bioRxiv · May 11, 2026 · PreprintMicrobiology