Author
The University of MelbourneORCID 0000-0001-8983-9790Unclaimed ORCID profile · follow to get notified of new preprints
5 papers
Recent·Most cited
Pailene S. Lim, Nicolai C Jung, Mikha Gabriela…·Stephen W. Scally
This study shows that targeting PTRAMP-CSS inhibits Plasmodium falciparum across liver, blood, and mosquito stages, supporting its potential as a multistage vaccine target.
Frankie M. T. Lyons, Jill Chmielewski, Mikha Gabriela…·Wai‐Hong Tham
This paper identifies nanobodies against Pfs48/45 that reduce malaria parasite transmission by inhibiting fertilization in Anopheles mosquitoes.
Frankie M. T. Lyons, Jill Chmielewski, Li‐Jin Chan…·Melanie H. Dietrich
The paper identifies nanobodies targeting domain 3 of PfHAP2 and determines its crystal structure, providing structural insights for transmission-blocking interventions against malaria.
Melanie H. Dietrich, Jill Chmielewski, Li‐Jin Chan…·Wai‐Hong Tham
The paper determines the cryo-EM structure of the Plasmodium falciparum Pfs230-Pfs48/45 fertilization complex and identifies domains critical for function and vaccine design.
Madeline G. Dans, Henni Piirainen, William Nguyen…·Paul R. Gilson
This study identifies MMV020291 as a compound that targets actin-1/profilin dynamics in Plasmodium falciparum, inhibiting red blood cell invasion and apicoplast segregation.