SigA forms amyloid fibrils and supports the competition of Shigella with the microbiota
Ahmad Sabbah, Julie Maucotel, Béatrice Roche, Mathieu Erhardt, Lorine Debande, Charlotte E. Chong, Antoine Schramm, Jérémy Fraering, Johana Chicher, Eric Ennifar, Kate S. Baker, Benoît Marteyn
This study shows SigA forms amyloid fibrils that help Shigella sonnei compete with the microbiota by forming complexes with colicin E1 that have antimicrobial activity.
bioRxiv · Jul 10, 2026 · PreprintMicrobiology