Johana Chicher

A Zur-dependent regulatory RNA involved in maintaining zinc homeostasis in Staphylococcus aureus

This study identifies two sRNAs in Staphylococcus aureus that regulate zinc homeostasis, showing their role in Zn-sparing responses and adaptation to metal limitation.

Universally conserved isoasparylation sustains ribosome biogenesis and function

The paper identifies isoaspartate modification of ribosomal protein uS11 as essential for ribosome biogenesis and function across all domains of life.

SigA forms amyloid fibrils and supports the competition of Shigella with the microbiota

This study shows SigA forms amyloid fibrils that help Shigella sonnei compete with the microbiota by forming complexes with colicin E1 that have antimicrobial activity.

PqqU (PA2289) is responsible for Pyrroloquinoline Quinone Uptake in Pseudomonas aeruginosa

This study identifies PqqU as the primary PQQ importer in P. aeruginosa, showing its essential role in PQQ uptake and metabolic adaptability.

Complete post-transcriptional modification profiles in individual Staphylococcus aureus tRNA species

The paper provides a comprehensive analysis of tRNA modifications in Staphylococcus aureus, revealing species-specific features and decoding dynamics.

Galectin-3 Mediated Endocytosis of the Orphan G-Protein-Coupled Receptor GPRC5A

This study identifies Galectin-3 as a novel ligand for GPRC5A, demonstrating its role in mediating endocytosis of the orphan GPCR in colorectal cancer cells.

Fatty Acid Synthase associates with nuclear-derived cytoplasmic dsRNA molecules and influences antiviral innate immune response

This study shows FASN depletion increases cytoplasmic endogenous dsRNA and enhances antiviral innate immune responses.

CLSY docking to Pol IV requires a conserved domain critical for small RNA biogenesis and transposon silencing.

The paper identifies a conserved CYC-YPMF motif in Pol IV critical for CLSY docking, essential for small RNA biogenesis and transposon silencing.

CLUH interactome reveals an association to SPAG5 and a proximity to the translation of mitochondrial protein

The paper identifies CLUH interactome in mammalian cells, revealing its association with SPAG5 and proximity to mitochondrial protein translation.

The TUTase URT1 connects decapping activators and prevents the accumulation of excessively deadenylated mRNAs to avoid siRNA biogenesis

This paper identifies URT1 as a TUTase that connects decapping activators and prevents excessive deadenylation of mRNAs, thereby avoiding siRNA biogenesis in Arabidopsis.

Proteasome subunit PSMC3 variants cause neurosensory syndrome combining deafness and cataract due to proteotoxic stress

The paper identifies a PSMC3 variant causing a neurosensory syndrome with deafness and cataracts due to proteotoxic stress and impaired proteasome function.

YBEY is an essential biogenesis factor for mitochondrial ribosomes

This study shows that human YBEY is essential for mitochondrial ribosome biogenesis, leading to respiratory deficiency and mitochondrial abnormalities.

RST1 and RIPR connect the cytosolic RNA exosome to the Ski complex in Arabidopsis

This study identifies RST1 and RIPR as proteins connecting the cytosolic RNA exosome to the Ski complex in Arabidopsis, showing their role in RNA quality control.