Cell BiologybioRxivPreprint
REGULATION OF HDL DYSFUNCTIONALITY BY PHOSPHATIDYLETHANOLAMINE LINKS POLY-UNSATURATED FATTY ACIDS WITH ATHEROSCLEROTIC CARDIOVASCULAR DISEASES
Malik Taradeh, Lise M. Hardy, Veronica D. Dahik…·Wilfried Le Goff
This study shows that arachidonic acid-containing phosphatidylethanolamine (ARA-PE) impairs HDL function, promoting atherosclerosis, while eicosapentaenoic acid-PE (EPA-PE) restores HDL function and may reduce ASCVD risk.
DOI 10.1101/2025.05.27.656492