Saema Ansar

This study shows that ischemic stroke causes changes in claudin-5 isoform expression in rats, which correlate with worse neurological outcomes and BBB dysfunction.

This study shows urban PM2.5 exposure impairs blood-brain barrier integrity and increases LOX-1 expression in human brain endothelial cells, suggesting a mechanism linking air pollution to cerebrovascular disease.

This study shows that inhibiting LOX-1 and MMP-9 with drugs improves outcomes after delayed rt-PA treatment in stroke by reducing hemorrhage and edema.