Marcelo Alves Soares

DeepVir: A reproducible workflow for large-scale viral dark matter discovery

DeepVir automates viral dark matter discovery by integrating homology-based alignment and HMM mining, identifying novel viral groups and lineages from bat transcriptomic data.

IL-6 is a Key Factor in the Formation of Gut Tissue Resident Memory T Cells from Naïve T cells

This study identifies IL-6 as a key factor in the differentiation of naive CD4+ T cells into gut tissue resident memory T cells (TRMs) through a combination of MAdCAM-1, TGF-β, and RA signaling.

HIHISIV: a database of gene expression in HIV and SIV host immune response

HIHISIV is a database that integrates and provides tools to analyze gene expression data from HIV and SIV host immune responses in humans and nonhuman primates.

Fecal Virome of Southeastern Maned Sloth (Bradypus crinitus)

The paper reports a viral metagenomic analysis of fecal samples from Southeastern Maned Sloths, identifying viral families and disease-associated bacterial genera.

Metagenomic analysis reveals novel dietary-related viruses in the gut virome of marmosets hybrids (Callithrix jacchus x Callithrix penicillata), Brazil

The paper identifies two novel insect viruses in marmoset fecal samples using viral metagenomics, suggesting potential insect hosts and expanding knowledge of viral diversity in Neotropical primates.

Discovery of two novel Torque Teno viruses in Callithrix penicillata provides insights on Anelloviridae diversification dynamics

The paper identifies two new Anelloviridae species in Callithrix penicillata using HTS and metagenomics, revealing host-virus co-diversification patterns.

Distinct co-expression networks using multi-omic data reveal novel interventional targets in HPV-positive and negative head-and-neck squamous cell cancer

This study identifies distinct co-expression networks in HPV+ and HPV- HNSCC using multi-omic data, revealing novel therapeutic targets and regulatory mechanisms.