Toby Wise

This study shows human claustrum neurons encode uncertainty and prediction errors during aversive learning, with distinct temporal profiles compared to anterior cingulate cortex.

The paper investigates how the medial prefrontal cortex (vmPFC) processes spatial margin of safety decisions, showing distinct roles for anterior and posterior regions in threat predictability and safety signaling.

This study extends an interoceptive learning task to measure prediction certainty continuously and applies a learning model to analyze how learning rates relate to stimuli valence and mental health factors.

The paper shows humans use socially adjusted value strategies in foraging, with fMRI revealing mid-cingulate and ventromedial prefrontal cortex encoding this value.

The paper shows that aversive learning in humans involves hippocampal reactivation and sequential replay of task states, with aversive outcomes enhancing reverse replay.

The paper links aversive learning processes to psychiatric symptoms using computational modeling and behavioral data from 400 subjects.