Author

Livius Penter

Humboldt-Universität zu BerlinORCID 0000-0002-9060-0207Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2 Genomics· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:statistical model· 3 Research Focus:cell-cell communication· 2 Assay:spatial transcriptomics· 2 Approach:benchmark study· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Approach:deep learning· 1

Frequent Co-Authors

Alicia PerzolliiD· 1 shared Andrej LissatiD· 1 shared Bianca F. GoemansiD· 1 shared C. Michael Zwaan· 1 shared Caleb A. LareauiD· 1 shared Cameron Y. ParkiD· 1 shared Catherine J. WuiD· 1 shared Chanell MangumiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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1 shared paperCancer Biology

Alicia PerzolliORCID

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3 papers

Recent·Most cited

Spatial multi-omics reveals targetable immunosuppressive macrophage T-cell interactions in human AML bone marrow

Merel van der Meulen, Emma S. Pool, Alicia Perzolli, Joost B. Koedijk, Eva M. Argiro, Li‐Ting Chen, Wim J. de Jonge, Elizabeth K. Schweighart, Marijn A. Vermeulen, Stefan Nierkens, Jana Ihlow, David A. Horst, Andrej Lissat, H. Josef Vormoor, Mirjam E. Belderbos, , Olaf T Heidenreich

This paper uses spatial multi-omics to identify immunosuppressive interactions between AML, macrophages, and T cells in bone marrow, highlighting the Galectin-9 - CD44/TIM-3 axis as a therapeutic target.

bioRxiv · Aug 7, 2026 · PreprintCancer Biology

Coordinated Immune Cell Networks in the Bone Marrow Microenvironment Define the Graft versus Leukemia Response with Adoptive Cellular Therapy

Katie Maurer, Cameron Y. Park, Shouvik Mani, Mehdi Borji, Florian Raths, Kenneth H. Gouin, Livius Penter, Yinuo Jin, Jia Yi Zhang, Crystal S. Shin, James R. Brenner, Jackson Southard, Sachi Krishna, Wesley S. Lu, Haoxiang Lyu, , Elham Azizi

The paper analyzes single-cell data from bone marrow samples to identify immune cell interactions that predict response to adoptive cellular therapy in myeloid leukemia.

Science Immunology · Jan 24, 2025Peer-reviewedCancer Biology

Artifacts in single-cell mitochondrial DNA mutation analyses misinform phylogenetic inference

Caleb A. Lareau, Michael Spencer Chapman, Livius Penter, Tal Nawy, Dana Pe’er, Leif S. Ludwig

The paper identifies artifacts in single-cell mtDNA variant calling that mislead phylogenetic inference and warns against using low-evidence variant workflows.

bioRxiv · Jul 28, 2024 · PreprintGenomics