Author

Jia Yi Zhang

Columbia University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Genomics· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:spatial transcriptomics· 3 Research Focus:cell-cell communication· 2 Approach:experimental assay· 2 Assay:ATAC-seq· 1 Research Focus:clustering· 1 Assay:CRISPR screen· 1 Approach:deep learning· 1

Frequent Co-Authors

Elham AziziiD· 3 shared Yinuo JiniD· 3 shared Abhishek Iyer· 1 shared Achille NazaretiD· 1 shared Ajna UzuniiD· 1 shared Alberto CicciaiD· 1 shared Angelo TaglialatelaiD· 1 shared Armando Del PortilloiD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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3 shared papersBioengineering

Elham AziziORCID

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Author profile →

3 papers

Recent·Most cited

LYNX: a deep generative model for linking spatial dynamics and cellinteractions in multimodal spatial data

Yinuo Jin, Joshua D. Myers, Presha Rajbhandari, Jia Yi Zhang, Kaylee W Fang, John Shaw Moazami, Noreen Hosny, Brent R. Stockwell, Elham Azizi

LYNX is a deep generative model that integrates multimodal spatial data to model spatial dynamics and cell-cell interactions across tissues.

bioRxiv · Jul 10, 2026 · PreprintBioengineering

Spatiotemporal Single-Cell Analysis Reveals T Cell Clonal Dynamics and Phenotypic Plasticity in Human Graft-versus-Host Disease

Lingting Shi, Ajna Uzuni, Ximi Kevin Wang, Michael Pressler, David W Harle, Shami Chakrabarti, Rodney Macedo, Kirubel Belay, Christian A. Gordillo, Erik Raps, Jia Yi Zhang, Achille Nazaret, Joy Linyue Fan, Yinuo Jin, Xin Shen, , Ran Reshef

This study uses spatiotemporal single-cell analysis to track T cell clonal dynamics and phenotypic plasticity in GVHD, revealing links between TCR features, clonal expansion, and disease severity.

bioRxiv · May 24, 2025 · PreprintSystems Biology

CRISPRmap: Sequencing-free optical pooled screens mapping multi-omic phenotypes in cells and tissue

Jiacheng Gu, Abhishek Iyer, Ben Wesley, Angelo Taglialatela, Giuseppe Leuzzi, Sho Hangai, Aubrianna Decker, Ruoyu Gu, Naomi Klickstein, Yuanlong Shuai, Kristina Janković, Lucy Parker-Burns, Yinuo Jin, Jia Yi Zhang, Justin Hong, , Jellert T. Gaublomme

CRISPRmap enables multi-omic optical pooled screens to map gene function in cells and tissue without sequencing, identifying pathogenic mutations and analyzing spatial phenotypes.

bioRxiv · Dec 26, 2023 · PreprintGenomics