Author

Lorena Magraner-Pardo

European Bioinformatics InstituteORCID 0000-0002-9064-4330Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:whole-exome sequencing· 2 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Approach:statistical model· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Aditi GulatiiD· 1 shared Andrew N.J. TuttiD· 1 shared Christopher J. LordiD· 1 shared Dragomir B. KrasteviD· 1 shared Éric Pujade-LauraineiD· 1 shared Feifei SongiD· 1 shared Hui Xiao· 1 shared Isabelle Laure Ray-CoquardiD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperCancer Biology

Aditi GulatiORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintMay 25, 2026

Reversion mutations define minimal BRCA1/2 requirements for therapy resistance

Lorena Magraner-Pardo, William Kerrison, Dragomir B. Krastev…·Christopher J. Lord

The paper identifies BRCA1/2 reversion mutations associated with drug resistance in cancer patients and highlights key domains critical for resistance.

DOI 10.64898/2026.05.22.727163

humanwhole-exome sequencing

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BioinformaticsScientific ReportsPeer-reviewedJul 12, 2021

A computational and structural analysis of germline and somatic variants affecting the DDR mechanism, and their impact on human diseases and prostate cancer progression

Lorena Magraner-Pardo, Roman Aleksander Laskowski, Tirso Pons, Janet M. Thornton

The paper analyzes germline and somatic variants in DDR genes, showing somatic variants cluster in functional regions and differ from germline variants in prostate cancer patients.

6 citations

humanwhole-exome sequencing

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