Cancer BiologybioRxivPreprint
Targeting HMGA1-driven leukemic transformation in myeloproliferative neoplasms with pacritinib
Can Hui Yang, Yajun Li, Kun Chen…·Zhiyuan Wu
This study identifies HMGA1 as a critical driver of MPN progression to sAML, showing it outperforms existing markers and is targeted by pacritinib to improve survival.
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