Author

Lídia Mateo

Institute for Research in BiomedicineORCID 0000-0002-9076-4025Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Patrick AloyiD· 2 shared Alba SalaiD· 1 shared Albert GandiosoiD· 1 shared Anna Maria AviñóiD· 1 shared Antonio BerengueriD· 1 shared Camille Stephan‐Otto AttoliniiD· 1 shared Carlos Gonzalez· 1 shared Chiara Lara Castellazzi· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersMolecular Biology

Patrick AloyORCID

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2 papers

Recent·Most cited

Systematic study of hybrid triplex topology and stability suggests a general triplex-mediated regulatory mechanism

Vito Genna, Guillem Portella, Alba Sala, Montserrat Terrazas, Israel Serrano‐Chacón, Javier González, Núria Villegas, Lídia Mateo, Chiara Lara Castellazzi, Mireia Labrador, Anna Maria Aviñó, Albert Gandioso, Patrick Aloy, Isabelle Brun Heath, Carlos Gonzalez, , Modesto Orozco

The paper systematically studies hybrid triplex topology and stability, revealing a regulatory mechanism in the human genome and transcriptome through triplex formation.

Nucleic Acids Research · Feb 27, 2025Peer-reviewedMolecular Biology

Identification and drug-induced reversion of molecular signatures of Alzheimers disease onset and progression in AppNL-G-F, AppNL-F and 3xTg-AD mouse models

Eduardo Pauls, Sergi Bayod, Lídia Mateo, Víctor Alcalde, Teresa Juan-Blanco, Marta Sánchez‐Soto, Takaomi C. Saido, Takashi Saito, Antonio Berenguer, Camille Stephan‐Otto Attolini, Marina Gay, Eliandre de Oliveira, Miquel Duran‐Frigola, Patrick Aloy

The paper identifies molecular signatures of Alzheimer's disease in AD mouse models and finds drugs that reverse these signatures and cognitive impairment.

Genome Medicine · Oct 26, 2021Peer-reviewedNeuroscience